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Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndrome
Colleen E. Clancy, … , Michihiro Tateyama, Robert S. Kass
Colleen E. Clancy, … , Michihiro Tateyama, Robert S. Kass
Published November 1, 2002
Citation Information:
J Clin Invest.
2002;
110(9)
:1251-1262.
https://doi.org/10.1172/JCI15928
.
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Article
Cardiology
Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndrome
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Abstract
Research Article
Authors
Colleen E. Clancy, Michihiro Tateyama, Robert S. Kass
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Figure 1
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Markov model of the cardiac Na
+
channel. The channel model contains background (upper nine states) and burst (lower four states) gating modes. The burst mode reflects a population of channels that transiently fail to inactivate.